AbstractGenetical genomics data present promising opportunities for integrating gene expression and genotype information. Lin et al. (2015) proposed an instrumental variables (IV) regression framework to select important genes with high-dimensional genetical genomics data. The IV regression addresses the issue of endogeneity caused by potential correlations between gene expressions and error te...
In statistical learning, various mathematical optimalities are used to characterize performances of different learning methods. They include minimax optimality from a worst-case standpoint and asymptotic efficiency from a rosy view that the regression function to be learned sits there to be discovered. When multiple models, e.g., trees, neural networks and support vector machines, are considere...